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      5. Imagine a World Free of IBD

      Imagine a World Free of IBD: IBD Stress Test QuickFire Challenge

      Imagine a World Free of IBD: IBD Stress Test QuickFire Challenge

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      As a growing population faces Inflammatory Bowel Disease (IBD), a worldwide community from over 50 countries came together to raise awareness and unite people worldwide in their fight against this disease on World IBD Day on May 19, 2018. Janssen Research & Development alongside Johnson & Johnson Innovation, JLABS joined in the conversation, urging action and announcing the IBD Stress Test Quickfire Challenge to award innovators who generate the best stress test solutions up to $50,000USD in grant funding, and help developing their ideas.

      IBD, which includes Crohn’s disease and ulcerative colitis, is characterized by chronic inflammation of the digestive tract. Symptoms can include severe abdominal pain, diarrhea, fatigue, and weight loss. Diagnosis is challenging and often delayed, leading many patients to progress to advanced stages of the disease, requiring surgery.

      And the numbers are growing – IBD affects more than 5 million people worldwide, and has demonstrated a rising incidence in newly industrialized countries in Africa, Asia, and South America.

      While there is no known cure, increasing evidence indicates that genetic and microbial factors, combined with environmental and lifestyle factors or “stressors” including infections, antibiotics, and diet, likely impact the development of IBD. Creating a systematic approach to tracking and analyzing a person’s responses to stressors could provide a path forward to better diagnose, treat, and prevent IBD.

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      Taking inspiration from stress tests such as the glucose tolerance test for diagnosing gestational diabetes and the cardiac stress test for diagnosing heart disease, we are looking to the best and brightest innovators across the globe to create an “IBD Stress Test” in an effort to better evaluate an individual’s immune and gastrointestinal health and ultimately predict risk of IBD.

      At Janssen Research & Development and Johnson & Johnson Innovation, JLABS, we have a successful history in creating new markets, delivering breakthrough innovation and establishing strong partnerships built on a shared vision. We believe a good idea can come from anywhere, and it’s our goal to break through the noise of the crowded landscape and to accelerate the development of novel technologies, treatments, and pharmaceuticals to provide solutions to patients.

      Together, let’s take a step towards a world free of IBD.

      Click here to learn more about the IBD Stress Test QuickFire Challenge and submit your Stress Test innovations by August 17, 2018. Follow @JLABS on Twitter for more information.

      Shannon Telesco, Ph.D.
      Shannon Telesco, Ph.D.
      Shannon Telesco, Ph.D.
      Shannon joined Janssen in 2011 with a focus on computational biology, the microbiome, and identification of biomarkers for patient stratification in inflammatory bowel disease (IBD). In 2014 Shannon led the development and implementation of the first clinical protocol for the Immunology Therapeutic Area designed to validate a biomarker of therapeutic response, which broke new ground in informing patient stratification efforts in IBD. In 2016 she took on a new role as the Lead for the IBD Interception program, which aims to create strategies for identifying people at risk of IBD and developing therapeutic interventions to prevent progression to clinical disease

      Shannon is passionate about disease prevention, especially the role of nutrition and diet. She graduated from Brown University with a B.S. in Biomedical Engineering in 2005. In addition to her mathematical and computational science skills, she developed a fascination with immunology and enjoyed her position as the Head Teaching Assistant in the Department of Immunology. Shannon went on to graduate from the University of Pennsylvania with a Ph.D. in Bioengineering in 2011.