Building our future legacy and extending our expertise to transform PAH into a
chronic, manageable condition.
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PAH affects people of all ages, impairing daily life and limiting survival. Our immediate goal is to prolong survival and we also aim to improve the quality of life for those living with this disease.
PAH can occur at all ages including in children, however most PAH patients are diagnosed between 50 and 65 years of age.1,2 The symptoms of PAH, such as shortness of breath, fatigue, chest pain and light-headedness, have a major impact on patients’ functioning and physical, psychological and social wellbeing.3
On average it takes two years from the onset of symptoms for PAH to be diagnosed,4 and many patients may go unidentified.5 Despite recent advances, PAH is a serious, progressive disease with no cure.6,7
With research and discovery programs shared across our therapeutic areas, we are committing significant discovery resources to uncover the most promising mechanisms that can modify the course of PAH. The goal for us is to reverse the underlying pathologies in PAH and resolve the disease itself.
To do so, we are tapping into our deep in-vitro and in-vivo expertise, as well as connecting with patient and research communities to fully understand the challenges and risks associated with PAH.
Other forms of pulmonary hypertension
Research to date has primarily focused on PAH but we have extended our research to include chronic thromboembolic pulmonary hypertension (CTEPH) and other types of PH.