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Immunology

Psoriasis, rheumatic diseases and inflammatory bowel disease share a common link – they are caused by an overreactive immune system that is out of balance. A person suffering from immunological disorders may experience pain, fatigue and difficulty performing simple tasks.

Every day, millions of people around the world are challenged by these debilitating diseases. At J&J Innovative Medicine, we are determined to discover new ways of restoring immune balance and to advance the search for better medicines to improve the lives of millions.
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Psoriasis
Psoriasis is a common dermatological disorder that affects around 2–3%1 of the world’s population. In Hong Kong, the prevalence of psoriasis is around 0.3–0.6%2.

People living with psoriasis have a poorer quality of life, often experiencing negative impacts on physical, social, emotional and mental wellbeing.
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Psoriatic arthritis
Up to 30% of people with psoriasis develop psoriatic arthritis (PsA), a chronic immune-mediated condition that is characterised by joint inflammation, most commonly of the hands and feet3. Other parts of the body may also be affected, such as the tendons and ligaments4.
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Inflammatory Bowel Disease
IBD is the chronic inflammation of the gastrointestinal tract, resulting in belly pain, diarrhea and rectal bleeding.

There are 6.8 million people5 living with IBD worldwide. This number is around 5,0006 in Hong Kong.

People with IBD live with pain and discomfort, which can complicate daily activities and disrupt work.

References

1 National Psoriasis Foundation. Psoriasis Statistics. The Impact of Psoriasis. Updated August 10, 2020. Accessed November 26, 2020. https://web.archive.org/web/20201122104257/https://www.psoriasis.org/psoriasis-statistics/.

2 News.gov.hk. Press release. Treatment for psoriasis patients. November 4, 2015. Accessed November 26, 2020. https://web.archive.org/web/20191101071825/https://www.info.gov.hk/gia/general/201511/04/P201511040716.htm.

3 Lenman M and Sonya A. Diagnosis and management of psoriatic arthropathy in primary care. British Journal of General Practise. 2014; 64(625); 424-425.

4 Arthritis Foundation. Metabolic Comorbidities of Psoriatic Arthritis. Available at https://www.arthritis.org/health-wellness/about-arthritis/related-conditions/other-diseases/metabolic-comorbidities-of-psoriatic-arthritis Accessed October 2022.

5 GBD 2017 Inflammatory Bowel Disease Collaborators. The global, regional, and national burden of inflammatory bowel disease in 195 countries and territories, 1990-2017: a systematic analysis for the Global Burden of Disease Study 2017. Lancet Gastroenterol Hepatol 2020; 5(1):17-30.

6 Ng SC, et al. Worldwide incidence and prevalence of inflammatory bowel disease in the 21st century: a systematic review of population-based studies. Lancet 2018; 390(10114):2769-2778.