Luc is a highly regarded expert in early clinical and non-clinical development with a strong track record in developing and applying translational experimental medicine models and biomarkers. He is a strong leader of people and teams, and has held management roles in clinical medicine and in global public health.
As leader of the Experimental Medicine group, Luc oversees design of clinical strategies and execution of clinical trials through Proof of Concept for all new molecular entities generated in the Janssen Neuroscience Therapeutic Area (TA). He has successfully integrated medical expertise into the drug discovery and early development process. Luc also serves as a member of the Janssen R&D Neuroscience Senior Leadership team.
He deployed the fast and lean process of clinical plan development, protocol development and trial execution, including lean trial visualization, and initiated several early development process improvement activities within and outside the Experimental Medicine group and across the five therapeutic areas. He served as Compound Development Team leader for several projects in early and late development. Luc maintains close and fruitful collaboration with external partners, the Johnson & Johnson Innovation Centers, and academic institutions.
Luc is chairman of the Neuroscience TA Discovery/Development Review Committee (DDRC) for Early Development. He also chairs the cross-TA Early Development Head Meeting, the Neuroscience Network Meeting in Beerse, and he is a member of the Johnson & Johnson First-In-Human Committee and the Janssen Campus R&D Senior Leadership Team in Beerse, Belgium.
Luc joined Janssen Research Foundation in Beerse in 1989 and advanced through a variety of management positions, including Clinical Research Manager and Senior Clinical Research Manager, Cardiovascular Medicine; Associate Director, Internal Medicine; Director, Global Gastroenterology; Senior Director, Global Experimental Therapeutics and Human Pharmacokinetics; Executive Director-Project Champion, Drug Evaluation; and Vice President, Experimental Medicine, Europe. He was named to his current role in 2009.
Before Luc joined Janssen, he practiced medicine and held management positions in clinical medicine and public health at St. Erasmus Hospital in Antwerp, Belgium, and The Ministry of Health, Zimbabwe, Africa.
Luc earned a medical degree from Catholic University, Louvain, Belgium, and completed postgraduate training in Tropical Medicine at Prince Leopold Institute, Antwerp. He also studied at the Vlerick School for Management, Leuven, Belgium. He is the author or coauthor of more than 75 publications and abstracts.