EMEA/Our innovation /Focus areas/Immunology

Immunology

We understand how distressing and debilitating immune-mediated inflammatory diseases (IMIDs) can be, which is why we strive to provide treatments that give you or your loved ones relief from the daily discomfort and stress that these conditions can pose. Rest assured, we are committed to building on our breakthroughs that have already changed the lives of millions of people around the world.
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Our commitment to patients
Johnson & Johnson is committed to help ease the challenges that people living with immune-mediated inflammatory diseases have to endure for the rest of their lives.

Our goal is to improve the diagnosis of immune-mediated inflammatory diseases, improve patients’ access to the best possible treatments and continue to provide new and better medicines.
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We never underestimate the human impact of immune-mediated inflammatory diseases
People living with immune-mediated inflammatory diseases can be affected for the rest of their lives, yet the impact of these conditions is dramatically underestimated. As some of these diseases are not readily recognised, people can suffer silently before eventually receiving treatment.
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Immune-mediated inflammatory diseases are the result of a relentless, internal, immunological ‘storm’, which can cause pain and discomfort that many people live with every day[1], [2], [3]. People may further experience stigma, isolation, decreased productivity and psychological issues[2], [4], [5], [6], [7]. And it’s not just them, their families and loved ones can be affected too[4] .


Our mission is clear: we won’t rest until we achieve a world free from immune-mediated inflammatory diseases.
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Our treatment areas
We are proud to have one of the strongest treatment portfolios for some of the most common immune-mediated inflammatory diseases.
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Dermatology
Our focus in Dermatology is inflammatory conditions of the skin.
June 17, 2024
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Rheumatology
Our focus in Rheumatology is currently inflammatory disorders of the joints and skin.
June 17, 2024
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Gastroenterology
Our focus in Gastroenterology is inflammatory bowel disease.
June 17, 2024
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Immunology facts
Living with an immune-mediated inflammatory disease has a similar impact on psychological and physical functioning to cancer, heart disease and hypertension.[9],[10]
They are debilitating and chronic diseases. Pain, fatigue and inability to perform everyday tasks are the most apparent symptoms.[11],[12], [13], [14], [15], [16], [17]
Many people also suffer from severe additional conditions as a result, such as depression.[13],[14], [18],[19]
Nearly 1 in 10 people in Europe are living with an immune-mediated inflammatory disease.[8]
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Johnson & Johnson is pioneering breakthroughs that change lives
We’ve always been innovative in our science, finding new and more effective ways to transform the course of immune-mediated inflammatory diseases and calm the inner battle waging within patients’ bodies.

Our breakthroughs have changed the lives of millions of people around the world living with some of the most common immune-mediated inflammatory diseases.
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We will continue our search for newer and better medicines
We’ve continued to advance our knowledge of the inflammatory process. We’ll carry on working on better therapies to try to stop and even cure immune-mediated inflammatory diseases, where the impact on patients is high and/or where there remains a need for better treatments.
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Working together to achieve a world where immune-mediated inflammatory diseases are a thing of the past
Our commitment to immune-mediated inflammatory diseases goes beyond our medicines. We support patients through collaborations with patient advocacy organisations.[22]

We invest heavily in continuous medical education of doctors and care providers, uniting different therapeutic areas to share expertise and best practices.
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We also bring together the brightest minds, including doctors, nurses, patients and patient groups, scientists and policy makers to turn scientific discoveries into treatment breakthroughs, and to ensure that people can benefit from the best treatments when they need them.
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Even though we have made great progress in the last decade for the treatment of immune-mediated inflammatory diseases, our work aims to raise the bar to make periods of disease remission more durable and allow patients with these debilitating diseases to lead normal lives.”
Ludovic de Beaucoudrey, PhD
JANSSEN THERAPEUTIC AREA LEAD, IMMUNOLOGY, EUROPE, MIDDLE EAST & AFRICA
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My IBD Journey
Looking for practical tips on living with inflammatory bowel disease (IBD)? Head to the My IBD Journey page, where you will find a series of short animations providing helpful advice about living well with IBD. These animations have been developed in association with the European Federation of Crohn’s and Ulcerative Colitis Associations ( EFCCA).
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Beyond Expectations
If you want to learn more about psoriasis or psoriatic arthritis, check out Beyond Expectations, our online patient portal for people living with psoriatic disease or who are interested in learning more about the disease and treatment options..
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References

[1] Lofvendahl, S., et al. Incremental costs for psoriasis and psoriatic arthritis in a population-based cohort in southern Sweden: is it all psoriasis-attributable morbidity? Journal of Rheumatology, 2016;43(3):640-647
[2] Lonffors, S., et al. IBD and health-related quality of life - discovering the true impact. Journal of Crohn’s and Colitis, 2014;8:1281-1286
[3] Najafi, S., et al. The potential similarities of COVID-19 and autoimmune disease pathogenesis and therapeutic options: new insights approach. Clin Rheumatol, 2020;39:3223–3235
[4] Eghlileb, A.M., et al. Psoriasis has a major secondary impact on the lives of family members and partners. Br J Dermatol, 2007;156(6):1245-50
[5] Dibley, L., et al. The experience of stigma in inflammatory bowel disease: An interpretive (hermeneutic) phenomenological study. J Adv Nurs, 2018;74:838-851
[6] Ograczyk, A., et al. Itch, disease coping strategies and quality of life in psoriasis patients. Postepy Dermatologi Alergologii, 2014;5:299-304
[7] Narayanan, S., et al. 2014. Disease burden and patient reported outcomes among patients with moderate to severe psoriasis: an ethnography study. Psoriasis (Auckl), 2014;5:1-7
[8] Cooper, G.S., et al. Recent Insights in the Epidemiology of Autoimmune Diseases: Improved Prevalence Estimates and Understanding of Clustering of Diseases. J Autoimmun. 2009;33(3-4):197-207
[9] Mease P. Assessing impact of Psoriatic Arthritis on Patient Function and Quality of Life: Lessons Learned from Other Rheumatologic Conditions. Semin Arthritis Rheum, 2009;38(4):320-335
[10] Walker, J., Littlejohn, G. Measuring quality of life in Rheumatic conditions. Clin Rheumatol, 2017; 26,p:671-673
[11] Lupus Foundation of America. Lupus facts and statistics. 2016. Available at: https://www.lupus.org/resources/lupus-facts-and-statistics. Accessed: October 2022
[12] Scotti, L., et al. Prevalence and incidence of psoriatic arthritis: a systematic review and meta-analysis. Semin Arth Rheum. 2018;48:28-34
[13] Bacconier, L., et al. Psychological distress over time in early rheumatoid arthritis: results from a longitudinal study in an early arthritis cohort. Rheumatology (Oxford) 2015;54(3):520-7
[14] Pompili, M., et al. Suicide risk and psychiatric comorbidity in patients with psoriasis. J Int Med Res. 2016;44(IS):61-66
[15] Amador-Patarroyo. M.J., et al. How does age at onset influence the outcome of autoimmune diseases? Autoimmune Dis, 2012;251730
[16] Habibi, F., et al. Quality of life in inflammatory bowel disease patients: A cross-sectional study. J Res Med Sci, 2017;22:104
[17] Becker, H.M., et al. Living with inflammatory bowel disease: A Crohn’s and Colitis Canada survey. Can J Gastroenterol Hepatol, 2015;29(2):77-84
[18] Shah, K., et al. Real-world burden of comorbidities in US patients with psoriatic arthritis. RMD Open, 2017;3(2):3
[19] Bernstein, C.N., et al. Increased Burden of Psychiatric Disorders in Inflammatory Bowel Disease. Inflamm Bowel Dis. 2019;25(2):360-368
[20] Liu JK. The history of monoclonal antibody development - Progress, remaining challenges and future innovations. Ann Med Surg (Lond). 2014;3(4):113-116
[21] EFCCA. My IBD Journey – animation series. 2019. Available at: https://efcca.org/projects/my-ibd-journey-animation-series. Accessed: October 2022

CP-459038
September 2024