Prostate cancer
We are leaders in prostate cancer, and are dedicated to helping delay disease progression.
We are exploring innovative approaches, such as using novel intermediate endpoints, which could transform the entire trajectory of cancer, and get one step closer to a cure. [3], [4]
References
[1] IARC. Online analysis table. Available at:
https://gco.iarc.fr/today/online-analysis-pie?v=2020&mode=cancer&mode_po.... Accessed January 2023.
[2] Smith-Palmer et al. Literature review of the burden of prostate cancer in Germany, France, the United Kingdom and Canada. BMC Urology. 2019 19, 19.
[3] Hait, W.N. et al. Moving upstream in anticancer drug development. Nat Rev. 2018; 18: 159-160
[4] Delgado, A, et al. Clinical endpoints in oncology - a primer. Am J Cancer Res. 2021; 11 (4): 1121-1131
[5] Golden Gate Cancer Center. Men with newly diagnosed prostate cancer – a primer. Available at:
https://www.goldengatecancercenter.com/blog/men-with-newly-diagnosed-prostate-cancer-a-primer. Accessed January 2023.
[6] European Federation of Pharmaceutical Industries and Associations. Precision Medicine. Availabe at:
https://www.efpia.eu/about-medicines/development-of-medicines/precision-medicine/#:~:text=%E2%80%9CPrecision%20medicine%20is%20a%20healthcare,resulting%20in%20improved%20health%20outcomes%E2%80%9D. Accessed February 2023
[7] ClinicalTrials.gov. A Study of Niraparib in Combination With Abiraterone Acetate and Prednisone Versus Abiraterone Acetate and Prednisone for Treatment of Participants With Metastatic Prostate Cancer (MAGNITUDE). Availabe at:
https://clinicaltrials.gov/ct2/show/NCT03748641?term=niraparib++magnitude&draw=2&rank=1 Accessed February 2023
[8] The Pharmaceutical Journal. The precision medicine approach to cancer therapy. Available at:
https://pharmaceutical-journal.com/article/research/the-precision-medicine-approach-to-cancer-therapy-part-1-solid-tumours Accessed January 2023
[9] John Hopkins. Prostate Cancer Prognosis. Available at:
https://www.hopkinsmedicine.org/health/conditions-and-diseases/prostate-cancer/prostate-cancer-prognosis. Accessed January 2023
[10] Cancer.net. Prostate Cancer: Statistics. Available at:
https://www.cancer.net/cancer-types/prostate-cancer/statistics. Accessed January 2023
[11] Seyhan, A.A., Carini, C. Are innovation and new technologies in precision medicine paving a new era in patients centric care?. J Transl Med 2019;17:114
[12] American Association for Cancer Research. Intercepting Cancer by Tackling Precancer. Available at:
https://www.aacr.org/blog/2021/01/15/intercepting-cancer-by-tackling-precancer/. Accessed January 2023
[13] Clinicaltrials.gov. Molecular Studies and Clinical Correlations in Human Prostatic Disease. Available at:
https://clinicaltrials.gov/ct2/show/NCT00578240. Accessed January 2023
[14] Smith, R, M, et al. Relationship Between Metastasis-free Survival and Overall Survival in Patients With Nonmetastatic Castration-resistant Prostate Cancer. Clinical Genitourinary Cancer. 2019; 18: 180-9
[15] Carles, J. et al. ORACULUM. A Retrospective Observational Epidemiological Study Using Artificial Intelligence and Natural Language Processing in Electronic Health Records to Characterize the Prostate Cancer pathway, Management and Outcomes in Europe, Middle East and Africa (EMEA region). Poster presentation at the European Society for Medical Oncology Virtual Congress, September 2020 (abstract #695TiP).
[16] Astex. Astex Announces New Drug Discovery Alliance with Janssen Pharmaceutica N.V. Available at:
https://astx.com/wp-content/uploads/2016/11//ASTX_News_2008_6_9_General_Releases.pdf. Accessed January 2023
[17] Ahuja AS. The impact of artificial intelligence in medicine on the future role of the physician. PeerJ. 2019;7:e7702.
[18] MELLODDY. MELLODDY Project meets its year one objective: deployment of the world’s first secure platform for multi-task federated learning in drug discovery among 10 pharmaceutical companies. Available at:
https://www.melloddy.eu/y1announcement. Accessed January 2023
[19] WebMD. What Is B-Cell Lymphoma. Available at:
https://www.webmd.com/cancer/lymphoma/what-is-b-cell-lymphoma. Accessed January 2023
[20] Zhang, et al. Clinicopathological factors in bladder cancer for cancer-specific survival outcomes following radical cystectomy: a systematic review and meta-analysis. Available at:
https://bmccancer.biomedcentral.com/articles/10.1186/s12885-019-5924-6. Accessed January 2023
[21] World Bladder Cancer Patient Coalition. Annual Meeting Report 2020. Available at:
https://worldbladdercancer.org/wp-content/uploads/2020/11/WBCPC-Annual-Meeting-2020-Report.pdf. Accessed January 2023
[22] Cancer.Net. Lung Cancer - Non-Small Cell: Statistics. Available at:
https://www.cancer.net/cancer-types/lung-cancer-non-small-cell/statistics. Accessed January 2023
CP-459038
September 2024