Skip to content

Search Results

No Results

    Recently Viewed

      Listening...

      Sorry, I don't understand. Please try again

      1. EMEA/
      2. Our innovation /
      3. Focus areas/
      4. Oncology /
      5. Prostate cancer/
      6. The power of targeted therapy

      The power of targeted therapy

      It is important to recognise that prostate cancer is an evolving disease. [8] Each person and their cancer are unique and, as such, we don’t take a one-size-fits-all approach to treatment.[9] We are precisely focused on[10] providing treatment options that delay progression, prolong life and support a better quality of life for our patients. [11]

      For patients diagnosed with an advanced form of the disease and for those at high-risk of disease progression, prostate cancer sadly, too often leads to death.[12],[13] This is why we are committed to providing innovative treatment solutions across all disease stages.[4],[5]

      [1] IARC. Online analysis table. Available at: https://gco.iarc.fr/today/online-analysis-pie?v=2020&mode=cancer&mode_po.... Accessed January 2023.
      [2] Smith-Palmer et al. Literature review of the burden of prostate cancer in Germany, France, the United Kingdom and Canada. BMC Urology. 2019 19, 19.
      [3] European Medicines Agency. Zytiga authorisation details. Availabe at: https://www.ema.europa.eu/en/medicines/human/EPAR/zytiga#authorisation-details-section. Accessed February 2023
      [4] European Medicines Agency. ERLEADA Summary of Product Characteristics. Available at: https://www.medicines.org.uk/emc/product/9832/smpc#gref. Accessed December 2022.
      [5] European Medicines Agency. ZYTIGA Summary of Product Characteristics. Available at: https://www.ema.europa.eu/en/documents/product-information/zytiga-epar-product-information_en.pdf. Accessed June 2021.
      [6] Hait, W.N. et al. Moving upstream in anticancer drug development. Nat Rev. 2018; 18: 159-160
      [7] Delgado, A, et al. Clinical endpoints in oncology - a primer. Am J Cancer Res. 2021; 11 (4): 1121-1131
      [8] Golden Gate Cancer Center. Men with newly diagnosed prostate cancer – a primer. Available at:https://www.goldengatecancercenter.com/blog/men-with-newly-diagnosed-prostate-cancer-a-primer. Accessed January 2023.
      [9] European Federation of Pharmaceutical Industries and Associations. Precision Medicine. Availabe at: https://www.efpia.eu/about-medicines/development-of-medicines/precision-medicine/#:~:text=%E2%80%9CPrecision%20medicine%20is%20a%20healthcare,resulting%20in%20improved%20health%20outcomes%E2%80%9D. Accessed February 2023
      [10] ClinicalTrials.gov. A Study of Niraparib in Combination With Abiraterone Acetate and Prednisone Versus Abiraterone Acetate and Prednisone for Treatment of Participants With Metastatic Prostate Cancer (MAGNITUDE). Availabe at: https://clinicaltrials.gov/ct2/show/NCT03748641?term=niraparib++magnitude&draw=2&rank=1 Accessed February 2023
      [11] The Pharmaceutical Journal. The precision medicine approach to cancer therapy. Available at: https://pharmaceutical-journal.com/article/research/the-precision-medicine-approach-to-cancer-therapy-part-1-solid-tumours Accessed January 2023
      [12] John Hopkins. Prostate Cancer Prognosis. Available at: https://www.hopkinsmedicine.org/health/conditions-and-diseases/prostate-cancer/prostate-cancer-prognosis. Accessed January 2023
      [13] Cancer.net. Prostate Cancer: Statistics. Available at: https://www.cancer.net/cancer-types/prostate-cancer/statistics. Accessed January 2023
      [14] Seyhan, A.A., Carini, C. Are innovation and new technologies in precision medicine paving a new era in patients centric care?. J Transl Med 2019;17:114
      [15] ClinicalTrials.gov. An Efficacy and Safety Study of JNJ-56021927 (Apalutamide) in High-risk Prostate Cancer Subjects Receiving Primary Radiation Therapy: ATLAS. Availabe at: https://clinicaltrials.gov/ct2/show/NCT02531516?term=erleada+atlas&draw=2. Accessed February 2023
      [16] American Association for Cancer Research. Intercepting Cancer by Tackling Precancer. Available at: https://www.aacr.org/blog/2021/01/15/intercepting-cancer-by-tackling-precancer/. Accessed January 2023
      [17] Clinicaltrials.gov. Molecular Studies and Clinical Correlations in Human Prostatic Disease. Available at: https://clinicaltrials.gov/ct2/show/NCT00578240. Accessed January 2023
      [18] Smith, R, M, et al. Relationship Between Metastasis-free Survival and Overall Survival in Patients With Nonmetastatic Castration-resistant Prostate Cancer. Clinical Genitourinary Cancer. 2019; 18: 180-9
      [19] Carles, J. et al. ORACULUM. A Retrospective Observational Epidemiological Study Using Artificial Intelligence and Natural Language Processing in Electronic Health Records to Characterize the Prostate Cancer pathway, Management and Outcomes in Europe, Middle East and Africa (EMEA region). Poster presentation at the European Society for Medical Oncology Virtual Congress, September 2020 (abstract #695TiP).
      [20] Astex. Astex Announces New Drug Discovery Alliance with Janssen Pharmaceutica N.V. Available at: https://astx.com/wp-content/uploads/2016/11//ASTX_News_2008_6_9_General_Releases.pdf. Accessed January 2023.
      [21] Ahuja AS. The impact of artificial intelligence in medicine on the future role of the physician. PeerJ. 2019;7:e7702.
      [22] MELLODDY. MELLODDY Project meets its year one objective: deployment of the world’s first secure platform for multi-task federated learning in drug discovery among 10 pharmaceutical companies. Available at: https://www.melloddy.eu/y1announcement. Accessed January 2023
      [23] WebMD. What Is B-Cell Lymphoma. Available at: https://www.webmd.com/cancer/lymphoma/what-is-b-cell-lymphoma. Accessed January 2023
      [24] Zhang, et al. Clinicopathological factors in bladder cancer for cancer-specific survival outcomes following radical cystectomy: a systematic review and meta-analysis. Available at: https://bmccancer.biomedcentral.com/articles/10.1186/s12885-019-5924-6. Accessed January 2023
      [25] World Bladder Cancer Patient Coalition. Annual Meeting Report 2020. Available at: https://worldbladdercancer.org/wp-content/uploads/2020/11/WBCPC-Annual-Meeting-2020-Report.pdf. Accessed January 2023
      [26] Cancer.Net. Lung Cancer - Non-Small Cell: Statistics. Available at:https://www.cancer.net/cancer-types/lung-cancer-non-small-cell/statistics. Accessed January 2023